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Showing posts from July, 2021

Towards A Sustainable Future

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  With pollution,  global climate change  , and other issues plaguing the health of  our surroundings  , industries operating  in several  sectors  round the  world are adopting greener solutions  to create  a sustainable future. The pharmaceutical industry, too, in recent years, has been gradually moving towards green manufacturing  to scale back  carbon footprints. But other opportunities for embracing sustainability  also can  be explored with plant-based natural ingredients. There are several vegetarian excipients available today  which will  replace conventional excipients. Naturally derived ingredients hold a promising future in drug product and supplement formulation. Gelatine – Ideal but not sustainable In the pharmaceutical industry, gelatine obtained from animal sources (bovine or porcine) has been a key pharmaceutical excipient that has been used as a gelling agent and for fabricating capsule shells.  it's  excellent gelling properties over  a good  pH range, its r

Sustainable Capsules For A Sustainable Future

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The market is flooded with a plethora of nutraceutical products offered by countless players giving rise to cut-throat competition. This industry is essentially consumer-driven and thus consumers play an important role choose the fate of those products. The expectations of health conscious consumers are many and their number is consistently on the increase .   Sustainability Is En Vogue “Sustainability” has been the buzzword in most industries for quite a while now. it's going to mean products developed using naturally-derived ingredients or minimally processed products. it's going to even ask products manufactured using fewer and known or recognizable ingredients. Currently there's no consensus on the usage of this term neither is its scope completely defined. However, as far as consumer choices are concerned, a clear shift towards vegetarianism has been observed. Animal-based products are now a strict no-no. Today consumers search for plant-based, natural ingredient

Polymers as synthetic immune stimulatory molecules in vaccine delivery

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  Over the  previous couple of  decades, vaccine delivery has evolved substantially, shifting from  the utilization  of conventional inactive or live attenuated pathogen to more advanced recombinant substances with adjuvants (the boosting agents that enhance immune stimulation). Polymers as adjuvants have augmented the formulation and delivery of vaccines,  resulting in  modern vaccination approaches through oral and nasal pathways.  the utilization  of polymeric substances in vaccines is gaining popularity, primarily  due to  their ability  to enhance  vaccine efficacy and achieve desired immune responses through targeted delivery. Diverse approaches for vaccine delivery that are currently available  are  listed in Table 1. Table 1: Different vaccine delivery techniques Technique   Example   Adjuvant  Poly lactic co-Glycolic Acid (PLGA), Alum, Liposome  Oral vaccine  Enteric-coated formulation  DNA vaccine