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Showing posts from April, 2021

Flexible Pharma Manufacturing – Need of the Hour

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Times are changing, and with it, the ways the pharma industry  wont to  operate  also are  changing. The so–called ‘’conservative’’ pharma manufacturers are now looking beyond  the normal  manufacturing model, exploring new avenues to accommodate unexpected sales forecasts  and little  volume production. As novel drug delivery therapies are evolving with time, pharma manufacturers now need manufacturing capabilities that are versatile enough to accommodate the market’s uncertain requirements and are more responsive. Flexible manufacturing is emerging as apt solution  which will  overcome these challenges successfully. Why flexible manufacturing Traditional manufacturing setup comprising different equipment pieces  for various  processes  are not any  longer enough  to satisfy  the assembly  requirements  of latest  drug products with small volume. Not only  is that this  mode inefficient, but it also  involves  more financial and physical resources. Also,  the subsequent  trends e

Developing fixed dose combinations using capsules

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  With few potential blockbuster drugs  within the  pharma pipeline  immediately  and therefore the  shrinking drug pipeline, many pharmaceutical companies are looking to expand their product portfolio from their existing molecules.  the foremost  common strategy is to expand into fixed-dose combination-based products which involves combining two or more existing molecules,  during a  single formulation.  this will  offer several advantages, such as, providing a synergistic therapeutic effect,  a far better  safety profile with fewer side effects, or  a far better  release profile.  a number of  these combinations  offers  multiple release profiles (where one drug  could also be  intended for immediate release  and therefore the  other for modified release or each of the constituent drug  could also be  designed for release at different locations within the  alimentary canal  .) Combination products  can also  help increase patient adherence by reducing pill burden. Hard capsules

Automated Washers – Changing the Paradigm of Pharmaceutical Cleaning

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  While industries worldwide are grappled with the COVID-19 pandemic, the pharma industry is on the frontline of the battle facing new challenges. These tough times have clearly shown that the pharma companies must take a relook at their resources and infrastructure to  affect  such crises  within the  future.  they need to  have  an answer  to tackle challenges  like  limited human resources, remote handling of systems, and uninterrupted production with maximum output. To confront these issues, automation is coming to the rescue. Automated systems are already taking  a big  load off the healthcare workers, providing invaluable assistance in  handling  the COVID-19 situation. Pharma manufacturers, too, are following  an equivalent  footsteps, adopting either fully automated processes or upgrading the routine operations where minimal human intervention is required. Cleaning is one operation of critical importance for pharmaceutical, biopharmaceutical, and research facilities because